SABIT PDMA SPPS Resins – Preview

SABIT-SPPS PDMA Resins are novel hydrophilic spherical resins aimed for solid phase peptide synthesis in aqueous and novel green solvents. All resins are made from scratch in-house, to ensure full control and reproducibility of each synthetic step of manufacturing of the products. It also enables us to provide custom-made variations and tailored solutions to specific peptide sequences.

Hydrophilic solid phase peptide resins may decrease aggregation, or other undesired effects observed in conventional PS-based or even PS-PEG based SPPS Resins. 

SABIT PDMA resins are potential alternatives to discontinued ChemMatrix resins and are alternatives to PEGA resins developed by the group of Meldal.

SABIT PDMA resins are co-polymers of dimethylacrylamide and bisacrylamide made with proprietary bead formation and novel resin architecture technology. Current variant has aminoethyl functional groups for coupling of a linker prior to peptide synthesis. 

First SPPS product has 0.5 mmol/g AM and a medium rigidity. Other resin rigidities, other loadings or other surface chemistries can be provided upon request.